| Week | Date | Visiter | Home | Bye |
| 1 | 3/14/2010 | North Texas Crunch | East Texas Drillers
| Missouri City Blitz Arlington Aviators Texas Krush Oklahoma Titans Texas Wranglers Southlake Pirates |
| 2 | 3/21/2010
| Texas Krush
| East Texas Drillers
| Oklahoma Titans Texas Wranglers Missouri City Blitz Southlake Pirates
North Texas Crunch Arlington Aviators
|
| 3 | 3/27/2010 | East Texas Drillers
Texas Wranglers Southlake Pirates | Missouri City Blitz Arlington Aviators Texas Krush | Oklahoma Titans
North Texas Crunch
|
| 4 | 4/03/2010
4/04/2010 | Missouri City Blitz Arlington Aviators Texas Wranglers
Oklahoma Titans
| Southlake Pirates Texas Krush North Texas Crunch East Texas Drillers
|
|
| 5 | 4/10/2010 | North Texas Crunch East Texas Drillers
Arlington Aviators | Texas Krush Southlake Pirates Missouri City Blitz | Texas Wranglers Oklahoma Titans
|
| 6 | 4/17/2010
4/18/2010
| Missouri City Blitz Oklahoma Titans Texas Wranglers Southlake Pirates
| North Texas Crunch Arlington Aviators Texas Krush East Texas Drillers
|
|
| 7 | 4/24/2010
4/25/2010
| Texas Krush
Texas Wranglers Southlake Pirates Oklahoma Titans
| North Texas Crunch Missouri City Blitz Arlington Aviators East Texas Drillers
|
|
| 8 | 5/01/2010 | Southlake Pirates Oklahoma Titans Missouri City Blitz | North Texas Crunch Texas Wranglers Texas Krush | Arlington Aviators East Texas Drillers
|
| 9 | 5/08/2010
5/09/2010
| North Texas Crunch Oklahoma Titans Texas Wranglers Missouri City Blitz
| Arlington Aviators Texas Krush Southlake Pirates East Texas Drillers |
|
| 10 | 5/15/2010 | Oklahoma Titans East Texas Drillers
Texas Krush | Missouri City Blitz Arlington Aviators Southlake Pirates | Texas Wranglers
North Texas Crunch
|
| 11 | 5/22/2010
5/23/2010
| Oklahoma Titans
Southlake Pirates Texas Wranglers
Arlington Aviators
| North Texas Crunch Missouri City Blitz Texas Krush East Texas Drillers
|
|
| 12 | 5/29/2010
5/30/2010
| Texas Krush Oklahoma Titans Missouri City Blitz Texas Wranglers
| North Texas Crunch Southlake Pirates Arlington Aviators East Texas Drillers
|
|
| 13 | 6/05/2010 | North Texas Crunch Texas Wranglers Oklahoma Titan | Missouri City Blitz Texas Krush Arlington Aviators | East Texas Drillers Southlake Pirates
|
| 14 | 6/12/2010 | Oklahoma Titans Texas Wranglers Arlington Aviators | North Texas Crunch Missouri City Blitz Southlake Pirates | East Texas Drillers Texas Krush
|
| 15 | 6/19/2010
6/20/2010
| North Texas Crunch Texas Wranglers Texas Krush Arlington Aviators
| Southlake Pirates Oklahoma Titans Missouri City Blitz East Texas Drillers
|
|
| 16 | 6/26/2010
6/27/2010
| Arlington Aviators Oklahoma Titans Texas Wranglers Missouri City Blitz
| North Texas Crunch Texas Krush Southlake Pirates East Texas Drillers
|
|
| 17 | 7/03/2010 | Playoffs | TBA | |
| 18 | 7/10/2010 | IIFA Alliance Bowl III | TBA | |